ባክቴሪያዎች ቅድመኑክለሳውያን (prokaryote microorganisms) ናቸው። ቅድመኑክለሳውያን ማለትም ፦ ኑክለስና ሌሎች በክርታስ የተሸፈኑ ክፍለ ህዋሳት የሌሏቸው መሆናቸው ከአርኬአዎች ጋር ያመሳስላቸዋል። እንደ ታዮማርጋሪታ ናሚቢየንሲስ እጅግ በጣም ጥቂት ወጣ ያሉ ዝርያዎች በስተቀር ባክቴሪያዎች በሙሉ ያለ ማይክሮስኮፕ የማይታዩ ደቂቅ ዘአካላት ናቸው።
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