'n Onkogeen is 'n geen wat kanker veroorsaak as dit gemuteer word of te veel daarvan in 'n sel uit gedruk word.
'n Besondere groep onkogene is die retrovirale onkogene waarmee retrovirusse 'n sel kan infekteer. 'n Voorbeeld is Rous se sarkomavirus (RSV) wat skielik tumore in ingeïnfekteerde diere veroorsaak
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