ଆକ୍ଲିଡିନିଅମ ବ୍ରୋମାଇଡ

Mr. Ibrahem/Aclidinium
Clinical data
Trade names	Bretaris Genuair, Eklira Genuair, Tudorza Pressair
Other names	Aclidinium bromide
AHFS/Drugs.com	Monograph
License data	US DailyMed: Aclidinium; US FDA: Aclidinium;
Routes of; ; administration	Inhalation
Drug class	Long-acting muscarinic antagonist (LAMA)
Legal status
Legal status	US: ℞-only ; EU: Rx-only ;
Pharmacokinetic data
Bioavailability	<5% (in system); ; 30% (in lung)
Metabolism	Ester hydrolysis
Elimination half-life	2–3 hrs
Duration of action	>24 hrs
Excretion	65% urine, 33% faeces
Identifiers
	IUPAC name [(8R)-1-(3-Phenoxypropyl)-1-azoniabicyclo[2.2.2]octan-8-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate bromide;
Chemical and physical data
Formula	C26H30BrNO4S2
Molar mass	564.55 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [Br-].O=C(O[C@@H]3C2CC[N+](CCCOc1ccccc1)(CC2)C3)C(O)(c4sccc4)c5sccc5;
	InChI InChI=1S/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1/t20?,22-,27?;/m0./s1 ; Key:XLAKJQPTOJHYDR-QTQXQZBYSA-M ;
	(what is this?) (verify)

ଆକ୍ଲିଡିନିଅମ ବ୍ରୋମାଇଡ
Clinical data
Trade names	Bretaris Genuair, Eklira Genuair, Tudorza Pressair
Synonyms	Aclidinium bromide
AHFS/Drugs.com	monograph
data	US DailyMed: Aclidinium;
Routes of; administration	Inhalation
Legal status
Legal status	US: ℞-only ; EU: Rx-only ;
Pharmacokinetic data
Bioavailability	<5% (in system); 30% (in lung)
Metabolism	Ester hydrolysis
Elimination half-life	2–3 hrs
Duration of action	>24 hrs
Excretion	65% urine, 33% faeces
Identifiers
	IUPAC name [(8R)-1-(3-Phenoxypropyl)-1-azoniabicyclo[2.2.2]octan-8-yl] 2-hydroxy-2,2-dithiophen-2-ylacetate bromide;
ECHA InfoCard	100.260.213
Chemical and physical data
Formula	C26H30BrNO4S2
Molar mass	୫୬୪.୫୫ g·mol−1
3D model (JSmol)	Interactive image;
	SMILES [Br-].O=C(O[C@@H]3C2CC[N+](CCCOc1ccccc1)(CC2)C3)C(O)(c4sccc4)c5sccc5;
	InChI InChI=1S/C26H30NO4S2.BrH/c28-25(26(29,23-9-4-17-32-23)24-10-5-18-33-24)31-22-19-27(14-11-20(22)12-15-27)13-6-16-30-21-7-2-1-3-8-21;/h1-5,7-10,17-18,20,22,29H,6,11-16,19H2;1H/q+1;/p-1/t20?,22-,27?;/m0./s1 ; Key:XLAKJQPTOJHYDR-QTQXQZBYSA-M ;
(verify)

ସାଧାରଣ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ମୁଣ୍ଡବିନ୍ଧା, କାଶ, ନାକ ଏବଂ ଗଳାର ପ୍ରଦାହ ଅନ୍ତର୍ଭୁକ୍ତ ହୋଇପାରେ । ଅନ୍ୟାନ୍ୟ ପାର୍ଶ୍ୱ ପ୍ରତିକ୍ରିୟାରେ ତରଳ ଝାଡ଼ା, ବ୍ରୋଙ୍କୋସ୍ପାଜ୍ମ ଏବଂ ୟୁରିନାରି ରିଟେନସନ ହୋଇପାରେ । ଏହା ଏକ ଦୀର୍ଘକାଳୀନ କାର୍ଯ୍ୟ କରୁଥିବା ମସ୍କାରିନିକ୍ ଆଣ୍ଟାଗୋନିଷ୍ଟ୍ (LAMA) |

ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଚିକିତ୍ସା ବ୍ୟବହାର ପାଇଁ ଆକ୍ଲିଡିନିଅମ ବ୍ରୋମାଇଡ ଅନୁମୋଦିତ ୨୦୧୨ ମସିହାରେ ହୋଇଥିଲା। ଯୁକ୍ତରାଜ୍ୟରେ ଏହାର ଏକ ମାସର ମୂଲ୍ୟ ୩୩ ପଉଣ୍ଡ । ଯୁକ୍ତରାଷ୍ଟ୍ରରେ ଏହି ରାଶି ୨୦୨୧ ସୁଦ୍ଧା ପ୍ରାୟ ୫୬୦ ଡଲାର ଅଟେ। ଏହା ଫର୍ମୋଟେରୋଲ ସହିତ ମଧ୍ୟ ଏକତ୍ର ଉପଲବ୍ଧ ।

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ଆକ୍ଲିଡିନିଅମ ବ୍ରୋମାଇଡ

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