Amphetamine (pronunciation: i/æmˈfɛtəmiːn/; contractit frae alpha‑methylphenethylamine) is a potent central nervous seestem (CNS) stimulant o the phenethylamine class that is uised in the treatment o attention deficit hyperacteevity disorder (ADHD) an narcolepsy.
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Dependence liability | Pheesical: none Psychological: moderate |
Addiction liability | Moderate |
Routes o admeenistration | Medical: oral, nasal inhalation Recreational: oral, nasal inhalation, insufflation, rectal, intravenous |
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Pharmacokinetic data | |
Bioavailability | Rectal 95–100%; Oral 75–100% |
Protein bindin | 15–40% |
Metabolism | CYP2D6, DBH, FMO3, XM-ligase, an ACGNAT |
Onset o action | Immediate |
Biological hauf-life | D-amph:9–11h; L-amph:11–14h |
Excretion | Renal; pH-dependent range: 1–75% |
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Synonyms | α-methylphenethylamine |
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PDB ligand | |
ECHA InfoCard | 100.005.543 |
Chemical and physical data | |
Formula | C9H13N |
Molar mass | 135.2084 g/mol |
3D model (Jmol) | |
Density | 0.9±0.1 g/cm3 |
Meltin pynt | 11.3 °C (52.3 °F) |
Bylin pynt | 203 °C (397 °F) |
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