Hong-sip-jia̍t (rheumatic fever) sī koên-téng ho͘-khip-tō khì hō͘ group A β hemolytic streptococcus oè--tio̍h só͘-lâi ín-khí ê chi̍t-chióng tî-hoat-sèng kap hui-hoà-lâng-sèng ê pēⁿ-piàn, pau-khoat sim-chōng, koan-chat, phoê-hā cho͘-chit, kap kî-thaⁿ chōng-khì chhiūⁿ náu, hì ê hoat-iām-sèng chi̍t-pēⁿ.
Lîm-chhn̂g-siōng chú-iàu ū sim-chōng-iām (carditis), to-hoat-sèng koan-chat-iām (polyarthritis), phoê-hā sió-kiat-chiat (subcutaneous nodules), erythema marginatum kap choea minor chia chē-chē ê chèng-thâu kap-kap-chò-hoé. I chú-iàu hoat-seng tī 3 hoè kàu 15 hoè ê gín-á-lâng.
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