Kolekaltziferol: Konposatu kimiko
Kolekaltziferola edo D3 bitamina D bitaminaren mota bat da.
Ezinbestekoa da kaltzioa eta fosforoa hezurretan finkatzeko. Organismoak bi bidetatik lor dezake: larruazaleko sintesia, eguzki-argiaren izpi ultramoreek 7-dehidrokolesterolean eragiten duten ekintzagatik, edo digestio-bidea, hura duten elikagaiak hartuz. Kolekaltziferola, gibelean hidroxilazio bidez, 25-hidroxikolekaltziferol (kaltzidiola) bihurtzen da. Hau, berriz ere, giltzurrunean hidroxilatzen denean, 1-25 dihidroxikolekalziferola (kaltzitriola) sortzen du. D bitaminaren eskasia prebenitzeko sendagai gisa erabiltzen dute.
| Kolekaltziferol | |
|---|---|
 | |
| Formula kimikoa | C27H44O |
| SMILES kanonikoa | 2D eredua |
| SMILES isomerikoa | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]\2[C@@]1(CCC/C2=C\C=C/3\C[C@H](CCC3=C)O)C |
| MolView | 3D eredua |
| Mota | [[(1S,3Z)-3-[(2E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol|(1S,3Z)-3-[(2E)-2-[(1R,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol]] (en)  eta cholecalciferol (undefined stereochemistry) (en) |
| Estereoisomeroa | [[(1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-Methyl-1-[(2R)-6-methylheptan-2-YL]-2,3,3A,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-OL|(1S,3Z)-3-[(2E)-2-[(1R,3AR,7AS)-7A-Methyl-1-[(2R)-6-methylheptan-2-YL]-2,3,3A,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-OL]] (en) , cholecalciferol (en) , (5Z,7E)-(3R)-9,10-seco-5,7,10(19)-cholestatrien-3-ol (en) eta (5E,7E)-(3R)-9,10-seco-5,7,10(19)-cholestatrien-3-ol (en) |
| Masa molekularra | 384,339216 Da |
| Erabilera | |
| Tratatzen du | minbizi, osteoporosi, gaixotasun kardiobaskular, giltzurrun-gutxiegitasun kroniko, skin benign neoplasm (en) , larruazaleko gaixotasun, lung benign neoplasm (en) , acropustulosis (en) eta Crohn's colitis (en) |
| Haurdunaldia | US pregnancy category A (en) |
| Rola | bone density conservation agents (en) , Bitamina, farmako esentzial eta primary metabolite (en) |
| Identifikatzaileak | |
| InChlKey | QYSXJUFSXHHAJI-YRZJJWOYSA-N |
| CAS zenbakia | 67-97-0 |
| ChemSpider | 4444353 |
| PubChem | 5280795 |
| Reaxys | 2339331 |
| Gmelin | 28940 |
| ChEBI | 1267613 |
| ChEMBL | CHEMBL1042 |
| ZVG | 100386 |
| EC zenbakia | 200-673-2 |
| ECHA | 100.000.612 |
| MeSH | D002762 |
| RxNorm | 2418 |
| Human Metabolome Database | HMDB0000876 |
| UNII | 1C6V77QF41 |
| NDF-RT | N0000146043 |
| KEGG | D00188 |
Erreferentziak
Kanpo estekak
Datuak: Q139347
Multimedia: Cholecalciferol / Q139347
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