Thomas Südhof (Göttingen, 22 de decembre de 1955) es un bioquimista american d'origina alemanda qu'es tanben professor a l'Universitat Stanford en Califòrnia.
Recebèt lo 7 d'octobre de 2013, amb los biologistas americans James E. Rothman e Randy Schekman, lo Prèmi Nobel de Fisiologia o Medecina de 2013. Anteriorament aviá ja recebut lo Prèmi Albert Lasker de Recerca Medicala Fondamentala.
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