Métaplasia Eriri Afọ
Métaplasia eriri afọ bụ mgbanwe (métaplasia) nke epithelium (na-abụkarị nke afọ ma ọ bụ esophagus) n'ime ụdị epithelium yiri nke a na-ahụ na eriri afọ.
Na esophagus, a na-akpọ nke a esophagos nke Barrett. A na-ahụ ọzịza na-adịghị ala ala nke ọrịa H. pylori na afọ na GERD na esophagus dị ka ndị isi na-akpata metaplasia na mmepụta adenocarcinoma. Na mbido, epithelium gbanwere yiri obere eriri afọ; na ọkwa ndị ọzọ ọ yiri eriri afọ. A na-akọwa ya site na ọdịdị nke Mkpụrụ ndụ iko na ngosipụta nke akara mkpụrụ ndụ eriri afọ dị ka ihe transcription, CDX2.
Ihe ize ndụ
Ọ bụ ezie na a kọrọ na mbụ na ndị agbụrụ East Asia nwere metaplasia eriri afọ nọ n'ihe ize ndụ dị ukwuu nke Ọrịa kansa afọ, ọ doro anya ugbu a na metaplasis eriri afọ bụkwa ihe ize ndụ na mpaghara ndị na-adịchaghị njọ dị ka Europe. Ihe ize ndụ maka ọganihu nke metaplasia eriri afọ na ọrịa kansa zuru oke bụ ịṅụ sịga na akụkọ ezinụlọ.
Ịnọgwụgwụ
Mmetụta nke eriri afọ nke nwere mmeghachi omume Mmebi DNA na-arụ ọrụ nwere ike ịnwe ogologo oge na ọnọdụ premalignant ruo mgbe mmebi ahụ ga-eme ka mmeghachihachi omume mmeji DNA na-eduga na mgbasawanye clonal na ọganihu na kansa. N'oge mmeghachi omume mmebi DNA, a na-egosipụta protein ndị na-achọpụta mmebi DNA ma na-eme ka mmeghachihachi omume dị ka mmezi DNA, ebe nyocha nke mkpụrụ ndụ ma ọ bụ apoptosis.
Ihe odide
Njikọ mpụga
- Ntuziaka AGA Clinical Practice na Nchịkwa nke Gastric Intestinal Metaplasia
- Intestinal metaplasia (nkọwa) - mondofacto.com.
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