泊马度胺: 化合物
泊马度胺（英語：Pomalidomide，商品名有Pomalyst、Imnovid）是一种含氮有机化合物，化学式为C13H11N3O4，可作为化疗药物，用于治疗多發性骨髓瘤和AIDS相关的卡波西肉瘤。
 | |
| 臨床資料 | |
|---|---|
| 商品名 | Pomalyst, Imnovid |
| AHFS/Drugs.com | Monograph |
| MedlinePlus | a613030 |
| 核准狀況 |
|
| 懷孕分級 |
|
| 给药途径 | By mouth |
| ATC碼 | |
| 法律規範狀態 | |
| 法律規範 |
|
| 藥物動力學數據 | |
| 生物利用度 | 73% (at least) |
| 血漿蛋白結合率 | 12–44% |
| 药物代谢 | Liver (mostly CYP1A2- and CYP3A4-mediated; some minor contributions by CYP2C19 and CYP2D6) |
| 生物半衰期 | 7.5 hours |
| 排泄途徑 | Urine (73%), faeces (15%) |
| 识别信息 | |
| |
| CAS号 | 19171-19-8  |
| PubChem CID | |
| IUPHAR/BPS | |
| DrugBank | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.232.884 |
| 化学信息 | |
| 化学式 | C13H11N3O4 |
| 摩尔质量 | 273.25 g·mol−1 |
| 3D模型（JSmol） | |
| 手性 | Racemic mixture |
| |
| |
参考文献
This article uses material from the Wikipedia 中文 article 泊马度胺, which is released under the Creative Commons Attribution-ShareAlike 3.0 license ("CC BY-SA 3.0"); additional terms may apply (view authors). 除非另有声明，本网站内容采用CC BY-SA 4.0授权。 Images, videos and audio are available under their respective licenses.
®Wikipedia is a registered trademark of the Wiki Foundation, Inc. Wiki 中文 (DUHOCTRUNGQUOC.VN) is an independent company and has no affiliation with Wiki Foundation.