Nectin

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There is a page named "Nectin" on Wikipedia

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  • Nectins and Nectin-like molecules (Necl) are families of cellular adhesion molecules involved in Ca2+-independent cellular adhesion. Nectins are ubiquitously...
  • Thumbnail for Nectin-3
    Nectin-3, also known as nectin cell adhesion molecule 3, is a protein that in humans is encoded by the NECTIN3 gene. Nectin-3 belongs to the family of...
  • Thumbnail for Poliovirus receptor-related 2
    Poliovirus receptor-related 2 (PVRL2), also known as nectin-2 and CD112 (formerly herpesvirus entry mediator B, HVEB), is a human plasma membrane glycoprotein...
  • Thumbnail for Measles morbillivirus
    cell adhesion molecule Nectin-4. For wild type and vaccine strains, extracellular domains of CD150 (SLAM or SLAMF1) and/or of nectin-4 (also called...
  • antibody-drug conjugate used for the treatment of urothelial cancer. It is a nectin-4-directed antibody and microtubule inhibitor conjugate. Enfortumab refers...
  • Thumbnail for Poliovirus receptor-related 1
    Poliovirus receptor-related 1 (PVRL1), also known as nectin-1 and CD111 (formerly herpesvirus entry mediator C, HVEC) is a human protein of the immunoglobulin...
  • Thumbnail for CD226
    mediates cellular adhesion to other cells bearing its ligands, nectin molecule CD112 and nectin-like protein CD155, that are broadly distributed on normal...
  • Thumbnail for Herpes simplex virus
    receptors include herpesvirus entry mediator (HVEM), nectin-1 and 3-O sulfated heparan sulfate. The nectin receptors usually produce cell-cell adhesion, to...
  • Thumbnail for Measles
    found on immune cells like B or T cells, and antigen-presenting cells, or nectin-4, a cellular adhesion molecule. Once bound, the fusion, or F protein helps...
  • Thumbnail for Synaptic stabilization
    ensure stability of synaptic components SynCAM’s (also known as Cadm or nectin-like molecules) are a specific type of synaptic CAM found in vertebrates...
  • Thumbnail for CD155
    leukemias: evidence for the involvement of the Poliovirus receptor (CD155) and Nectin-2 (CD112)". Blood. 105 (5): 2066–73. doi:10.1182/blood-2004-09-3548. PMID 15536144...
  • ASG-22M6E): product candidate for the treatment of solid tumours (targets Nectin-4 in bladder, breast, lung and pancreatic cancer); developed in 50-50 partnership...
  • Thumbnail for Cell junction
    filaments Integrins EC matrix Adherens junctions (Adhesion belt, Focal adhesion) Actin filaments Cadherin / Integrin / Nectins Other cells / EC matrix...
  • Thumbnail for Herpes
    of cases. Virus enters into susceptible cells by entry receptors such as nectin-1, HVEM and 3-O sulfated heparan sulfate. Infected people who show no visible...
  • including ovarian and pancreatic cancer. The conjugate consists of a human anti-nectin-4 antibody linked to the cytotoxic agent MMAE, which is released after internalization...
  • Thumbnail for Vaccine hesitancy
    PMC 4222184. PMID 25080364. Noyce RS, Richardson CD (September 2012). "Nectin 4 is the epithelial cell receptor for measles virus". Trends in Microbiology...
  • Thumbnail for Poliovirus
    PMC 7086627. PMID 19495937. Mueller S, Wimmer E (August 2003). "Recruitment of nectin-3 to cell-cell junctions through trans-heterophilic interaction with CD155...
  • in aid of viral entry" (2001) "Striking similarity of murine nectin-1alpha to human nectin-1alpha (HveC) in sequence and activity as a glycoprotein D receptor...
  • Thumbnail for List of therapeutic monoclonal antibodies
    humanized TWEAK receptor cancer etc. Enfortumab vedotin Padcev mab human nectin-4 Y urothelial cancer Enlimomab pegol mab mouse ICAM-1 (CD54) Enoblituzumab...
  • associated with forms of anemia, myelofibrosis and thrombocythemia. CD111 Nectin-1 or Herpesvirus entry mediator C (HveC), encoded by the PVRL1 (Poliovirus...
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