Arrestin Tissue distribution
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Arrestins (abbreviated Arr) are a small family of proteins important for regulating signal transduction at G protein-coupled receptors. Arrestins were...
Beta-arrestin-2, also known as arrestin beta-2, is an intracellular protein that in humans is encoded by the ARRB2 gene. Members of arrestin/beta-arrestin...
Blasi A (May 1993). "Molecular analysis of human beta-arrestin-1: cloning, tissue distribution, and regulation of expression. Identification of two isoforms...- activates cAMP. The V2R continues to activate Gs after being internalized by β-arrestin rather than being desensitized. This internalized Gs signaling by V2R is...
phosphorylation, the GPCR's affinity for β-arrestin (β-arrestin-1/2 in most tissues) is increased, at which point β-arrestin may bind and act to both sterically...
Thrombin receptor (section Tissue distribution)phosphorylation of activated receptors by kinases, which increases affinity for arrestin. Arrestin prevents protein-receptor interaction and the receptor becomes dephosphorylated...
TAAR1 (section Tissue distribution)Clinical Pharmacology. Retrieved 16 July 2018. Tissue Distribution CNS (region specific) & several peripheral tissues: Stomach > amygdala, kidney, lung, small...
disulfide bridge, Asp-Arg-Tyr, which is responsible for association with arrestin and, Lys/Arg-Lys/Arg-X-X-Lys/Arg, which interacts with G-proteins. The...
5961. PMID 10820279. Bennett TA, Maestas DC, Prossnitz ER (Aug 2000). "Arrestin binding to the G protein-coupled N-formyl peptide receptor is regulated...
beta-arrestin-mediated endocytosis (and intracellular accumulation) of AVPR1A, since AVPR2 is far less likely to dissociate from beta-arrestin. The activity/genetic...
Κ-opioid receptor (section Distribution)6'-Guanidinonaltrindole (6'-GNTI) – biased ligand: G protein agonist, β-arrestin antagonist Butorphan – full agonist Butorphanol – partial agonist Cyclorphan...- Urotensin-II receptor (section Tissue distribution)also promotes beta arrestin translocation. Beta arrestin is important for ceasing the response of a receptor to a stimuli. Beta arrestin also brings with...
- receptor will lead to receptor phosphorylation that recruits β-arrestin 1 and β-arrestin 2, resulting in a loss of responsiveness and internalization (endocytosis...
RALGDS gene in humans. RALGDS has been shown to interact with: Arrestin beta 1, Arrestin beta 2, HRAS, KRAS, MRAS, RAP1A, RAP2A, RAPGEF2, and RRAS. GRCh38:...
5-HT2A receptor (section Distribution)Whole-body distribution of the 5-HT2A/2C receptor agonist, [11C]Cimbi-36 show uptake in several internal organs and brown adipose tissue (BAT), but it...
Enhancement of lipolysis in adipose tissue. Thermogenesis in skeletal muscle It is located mainly in adipose tissue and is involved in the regulation of...
Shichida Y, Oishi T, Tamotsu S, Terakita A (January 2011). Barnes S (ed.). "β-arrestin functionally regulates the non-bleaching pigment parapinopsin in lamprey...
archaea - arginine - argipressin - aromatic amine - aromatic compound - arrestin - Arrhenius equation - aryl hydrocarbon receptor - asparagine - aspartic...
δ-opioid receptors have been shown to interact with β2 adrenergic receptors, arrestin β1 and GPRASP1. κ-opioid receptor μ-opioid receptor GRCh38: Ensembl release...
receptor-like receptor, receptor activity-modifying protein 1 (RAMP1), and beta-arrestin". J. Biol. Chem. 276 (45): 42182–90. doi:10.1074/jbc.M107323200. PMID 11535606...
