Quarterbacks - 28 James Cook
- 41 Reggie Gilliam FB
- 20 Nyheim Hines
- 25 Taiwan Jones
- 26 Devin Singletary
Wide receivers - 13 Gabe Davis
- 14 Stefon Diggs
- 6 Isaiah McKenzie
- 10 Khalil Shakir
Tight ends | | Offensive linemen - 71 Ryan Bates G
- 65 Ike Boettger G
- 79 Spencer Brown T
- 73 Dion Dawkins T
- 68 Bobby Hart G
- 60 Mitch Morse C
- 67 Justin Murray T
- 77 David Quessenberry T
- 76 Rodger Saffold G
- 75 Greg Van Roten C
Defensive linemen - 55 Carlos Basham Jr. DE
- 57 A. J. Epenesa DE
- 92 DaQuan Jones DT
- 90 Shaq Lawson DE
- 91 Ed Oliver DT
- 97 Jordan Phillips DT
- 50 Gregory Rousseau DE
- 99 Tim Settle DT
| | Linebackers - 43 Terrel Bernard OLB
- 53 Tyrel Dodson MLB
- 49 Tremaine Edmunds MLB
- 52 A. J. Klein MLB
- 44 Tyler Matakevich MLB
- 58 Matt Milano OLB
- 54 Baylon Spector OLB
Defensive backs - 24 Kaiir Elam CB
- 3 Damar Hamlin FS
- 30 Dane Jackson CB
- 4 Jaquan Johnson SS
- 7 Taron Johnson CB
- 39 Cam Lewis CB
- 31 Dean Marlowe FS
- 36 Jared Mayden FS
- 33 Siran Neal CB
- 21 Jordan Poyer SS
- 27 Tre'Davious White CB
Special teams | | | | Reserve lists - 47 Christian Benford CB (IR)
 - 80 Jamison Crowder WR (IR)
- 72 Tommy Doyle T (IR)
- 23 Micah Hyde FS (IR)
- 15 Jake Kumerow WR (IR)
- 40 Von Miller OLB (IR)
Practice squad - 70 Alec Anderson T
- 51 Eli Ankou DT (Injured)
- 5 Matt Barkley QB
- 11 Cole Beasley WR
- 94 Cortez Broughton DT
- 16 John Brown WR
- 96 Brandin Bryant DT
- 84 Zach Davidson TE
- 87 Tanner Gentry WR
- 42 Joe Giles-Harris OLB
- 46 Ja'Marcus Ingram CB
- 22 Duke Johnson RB
- 19 KeeSean Johnson WR
- 59 Kingsley Jonathan DE
- 56 Mike Love DE
- 32 Kyler McMichael CB
- 74 Ryan Van Demark T
Rookies in italics Roster updated January 2, 2023 53 active, 6 inactive, 16 practice squad (+1 exempt) → AFC rosters → NFC rosters |
