Telomere-Associated Protein Rif1

Telomere-associated protein RIF1 is a protein that in humans is encoded by the RIF1 gene.

RIF1
Identifiers
AliasesRIF1, replication timing regulatory factor 1
External IDsOMIM: 608952 MGI: 1098622 HomoloGene: 41231 GeneCards: RIF1
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001177663
NM_001177664
NM_001177665
NM_018151

NM_175238
NM_001355414
NM_001355415

RefSeq (protein)

NP_001171134
NP_001171135
NP_001171136
NP_060621

NP_780447
NP_001342343
NP_001342344

Location (UCSC)Chr 2: 151.41 – 151.51 MbChr 2: 51.96 – 52.01 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

RIF1 and RIF2 cap the chromosome ends (telomeres) in yeast. In higher eukaryotes, Rif1 is involved in DNA damage response, organisation of chromatin architecture and the regulation of replication timing. RIF1 has been shown to bind to RNA in the nucleus.

References

Further reading

Tags:

GeneProtein

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