Troponin

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  • Thumbnail for Troponin
    Troponin, or the troponin complex, is a complex of three regulatory proteins (troponin C, troponin I, and troponin T) that are integral to muscle contraction...
  • Thumbnail for Troponin I
    Troponin I is a cardiac and skeletal muscle protein family. It is a part of the troponin protein complex, where it binds to actin in thin myofilaments...
  • Thumbnail for Troponin T
    Troponin T (shortened TnT or TropT) is a part of the troponin complex, which are proteins integral to the contraction of skeletal and heart muscles. They...
  • Thumbnail for Troponin C
    Troponin C is a protein which is part of the troponin complex. It contains four calcium-binding EF hands, although different isoforms may have fewer than...
  • Thumbnail for Troponin C type 1
    Troponin C, also known as TN-C or TnC, is a protein that resides in the troponin complex on actin thin filaments of striated muscle (cardiac, fast-twitch...
  • is introduced into the cytosol, it binds to the troponin of thin filaments, which causes the troponin-tropomyosin complex to change shape and allow the...
  • Thumbnail for Unstable angina
    release detectable quantities of a marker of injury, typically troponin T or troponin I. Unstable angina is considered to be present in patients with...
  • Thumbnail for TNNT2
    muscle troponin T (cTnT) is a protein that in humans is encoded by the TNNT2 gene. Cardiac TnT is the tropomyosin-binding subunit of the troponin complex...
  • Thumbnail for TNNI3
    Troponin I, cardiac muscle is a protein that in humans is encoded by the TNNI3 gene. It is a tissue-specific subtype of troponin I, which in turn is a...
  • Thumbnail for Cardiac marker
    the markers currently used are enzymes. For example, in formal usage, troponin would not be listed as a cardiac enzyme. Measuring cardiac biomarkers can...
  • Thumbnail for Muscle contraction
    adenosine diphosphate (ADP) + Pi. Two Ca2+ ions bind to troponin C on the actin filaments. The troponin-Ca2+ complex causes tropomyosin to slide over and unblock...
  • Thumbnail for TNNI1
    Troponin I, slow skeletal muscle is a protein that in humans is encoded by the TNNI1 gene. It is a tissue-specific subtype of troponin I, which in turn...
  • Thumbnail for Myocardial infarction
    (STEMI), if ST elevation is present. Commonly used blood tests include troponin and less often creatine kinase MB. Treatment of an MI is time-critical...
  • Thumbnail for Troponin C, skeletal muscle
    Troponin C, skeletal muscle is a protein that in humans is encoded by the TNNC2 gene. Troponin (Tn), is a key protein complex in the regulation of striated...
  • Thumbnail for TNNI2
    Troponin I, fast skeletal muscle is a protein that in humans is encoded by the TNNI2 gene. The TNNI2 gene is located at 11p15.5 in the human chromosomal...
  • Thumbnail for CPK-MB test
    [citation needed] In some locations, the test has been superseded by the troponin test. However, recently, there have been improvements to the test that...
  • autoimmune hepatitis. These antibodies can be directed against actin, troponin, and tropomyosin. Dawkins, RL; Joske RA (June 1973). "Immunoglobulin deposition...
  • Thumbnail for Isotropic bands
    from binding to myosin. It attaches to troponin, which secures it in place. During muscle relaxation, the troponin-tropomyosin complex inhibits myosin heads...
  • surgery, also known as MINS, refers to at least one elevated post-operative troponin level presumed to be of an ischemic mechanism. There is an absence of any...
  • Thumbnail for Myofilament
    sarcoplasmic reticulum into the sarcoplasm and subsequently bind to troponin. Troponin and the associated tropomyosin undergo a conformational change after...
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