Thymocyte

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  • A thymocyte is an immune cell present in the thymus, before it undergoes transformation into a T cell. Thymocytes are produced as stem cells in the bone...
  • Anti-thymocyte globulin (ATG) is an infusion of horse or rabbit-derived antibodies against human T cells and their precursors (thymocytes), which is used...
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    T cells, the thymocytes must undergo multiple DN stages as well as positive selection and negative selection. Double negative thymocytes can be identified...
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    made up of immature T cells called thymocytes, as well as lining cells called epithelial cells which help the thymocytes develop. T cells that successfully...
  • Dinitrotoluene, a chemical precursor to TNT Double-negative T cell, a thymocyte in an early stage of development Dysembryoplastic neuroepithelial tumour...
  • immunosuppressive drugs—typically either anti-lymphocyte globulin or anti-thymocyte globulin—combined with corticosteroids, chemotherapy, and ciclosporin...
  • by TEC network filled with thymocytes (blood cell precursors of T cells) in different developing stages. TECs and thymocytes are the most important components...
  • dendritic cells, and B lymphocytes, and provide signals essential for thymocyte development and the homeostasis of the thymic stroma. The thymus is a...
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    needed] Anti-thymocyte globulin, an immunosuppressive agent that selectively destroys T lymphocytes is being studied for use in CIDP. Anti-thymocyte globulin...
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    2014). "Positive and negative selection of the T cell repertoire: what thymocytes see (and don't see)". Nature Reviews. Immunology. 14 (6): 377–91. doi:10...
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    epithelium which is often considered an epithelial organ. T cells mature from thymocytes, proliferate, and undergo a selection process in the thymic cortex before...
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    "Effects of altered glucocorticoid sensitivity in the T cell lineage on thymocyte and T cell homeostasis". FASEB Journal. 16 (7): 727–729. doi:10.1096/fj...
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    cytoplasm of pro-thymocytes, the stem cells from which T-cells arise in the thymus. The pro-thymocytes differentiate into common thymocytes, and then into...
  • cortico-medullary junction. They have their own nucleus and are known to internalize thymocytes through extensions of plasma membrane. The cell surfaces of TNCs and their...
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    thyroid gland injuries (including hepatocarcinoma),[citation needed] and thymocyte apoptosis. Other effects of PCBs in animals include changes in the immune...
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    Thymocyte selection-associated high mobility group box protein TOX is a protein that in humans is encoded by the TOX gene. TOX drives T-cell exhaustion...
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    cells, and increases the ability of dendritic cells to convert naive thymocytes to a Foxp3+ regulatory T cell lineage. It is unknown if this is the physiological...
  • thymus. So many thymocytes (T cells) die during the maturation process because there is intensive screening to make sure each thymocyte has the ability...
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    cells, B-lymphocytes (through surface immunoglobulins), fibroblasts, rat thymocytes, human fetal (but not adult) intestinal epithelial cells, and adipocytes...
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    also identifies the earliest thymocyte progenitors in the thymus—early T lineage progenitors (ETP/DN1) and DN2 thymocytes express high levels of c-Kit...
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