Pluripotency

totipotency to designate a cell with the most differentiation potential, pluripotency, multipotency, oligopotency, and finally unipotency. Totipotency (Latin:...

iPSCs are typically derived by introducing products of specific sets of pluripotency-associated genes, or "reprogramming factors", into a given cell type...

share many similar properties, such as pluripotency and differentiation potential, the expression of pluripotency genes, epigenetic patterns, embryoid body...

pluripotency, an emerging and very promising field of regenerative medicine. LIF (Leukemia inhibitory factor) signaling, which maintains pluripotency...

embryonic stem cells and are necessary for the maintenance of their pluripotency. It is thought that they achieve this through alterations in chromatin...

ability to maintain pluripotency throughout embryonic development. Recently, it has been noted that OCT-4 not only maintains pluripotency in embryonic cells...

embryos express pluripotency marker genes such as POU5F1, NANOG and Rex1. Derived human ESC lines also expressed specific pluripotency markers: TRA-1-60...

of pluripotency maintenance genes. The expression of transcription factors such as the SON factor and epigenetic modifiers regulate the pluripotency of...

The pluripotency of biological compounds describes the ability of certain substances to produce several distinct biological responses. Pluripotent is also...

mechanisms may block conversion to pluripotency. Research is underway to generate stimulus-triggered acquisition of pluripotency (STAP) cells using human tissue:...

cells that in subsequently differentiate into the desired cell types. Pluripotency distinguishes embryonic stem cells from adult stem cells, which are multipotent...

more restricted in the differentiation potential and eventually lose pluripotency. In 1962, John B. Gurdon demonstrated that the nucleus from a differentiated...

(ESCs). Pluripotency in EpiSCs is essentially different from that of embryonic stem cells. The pluripotency of EpiSCs is primed pluripotency: primed to...

Oct4: Oct4 is expressed in the ICM and participate in maintaining its pluripotency, a role that has been recapitulated in ICM derived mouse embryonic stem...

as a major determinant for transition between totipotency and naïve pluripotency states. From 2013, Hanna worked as the Robertson Stem Cell Investigator...

Developmental pluripotency-associated protein 2 is a protein that in humans is encoded by the DPPA2 gene. GRCh38: Ensembl release 89: ENSG00000163530 –...

coding potential, have been found associated with regulation of stem cell pluripotency and cell division. The third major group of regulatory RNAs is called...

expression of pluripotency. The main indicator that the initiation phase has completed is that the first genes associated with pluripotency are expressed...

has indicated that it was possible to replicate cells and reestablish pluripotency, or "the potential of an embryonic cell to grow into any one of the numerous...

turn into neurons by virtue of their stem cell-like characteristic of pluripotency. Like all animal cells, the cell body of every neuron is enclosed by...