Phosphatidylinositol 4,5 Bisphosphate Functions
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Phosphatidylinositol 4,5-bisphosphate or PtdIns(4,5)P2, also known simply as PIP2 or PI(4,5)P2, is a minor phospholipid component of cell membranes. PtdIns(4...
4)P2 Phosphatidylinositol 3,5-bisphosphate, also known as PtdIns(3,5)P2 or PI(3,5)P2 Phosphatidylinositol 4,5-bisphosphate, also known as PtdIns(4,5)P2...- Phosphatidylinositol-4,5-bisphosphate 4-phosphatase (EC 3.1.3.78, phosphatidylinositol-4,5-bisphosphate 4-phosphatase I, phosphatidylinositol-4,5-bisphosphate...
Phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) is one of the seven phosphoinositides found in eukaryotic cell membranes. In quiescent cells, the...
Phosphatidylinositol (3,4)-bisphosphate (PtdIns(3,4)P2) is a minor phospholipid component of cell membranes, yet an important second messenger. The generation...- In enzymology, a phosphatidylinositol-4,5-bisphosphate 3-kinase (EC 2.7.1.153) is an enzyme that catalyzes the chemical reaction: ATP + 1-phosphatidyl-1D-myo-inositol...
phosphoinositide 3-kinases' (PI 3-kinases) phosphorylation of phosphatidylinositol (4,5)-bisphosphate (PIP2). It is a phospholipid that resides on the plasma...- fifth hydroxyl of the myo-inositol ring to form phosphatidylinositol 4,5-bisphosphate. Phosphatidylinositol 4-Phosphate-5 kinase (PI4P5K) or PIP5K or PI5K...
Phosphoinositide 3-kinase (redirect from 1-phosphatidylinositol 3-kinase)I PI3Ks catalyze the conversion of phosphatidylinositol (4,5)-bisphosphate (PI(4,5)P2) into phosphatidylinositol (3,4,5)-trisphosphate (PI(3,4,5)P3)...- The phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha (the HUGO-approved official symbol = PIK3CA; HGNC ID, HGNC:8975), also called...
Phosphoinositide phospholipase C (redirect from 1-phosphatidyl-1D-myo-inositol-4,5-bisphosphate inositoltrisphosphohydrolase)phosphoinositidase C, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase, monophosphatidylinositol phosphodiesterase, phosphatidylinositol phospholipase...- Gq alpha subunit (section Function)phospholipase C (PLC-β) enzymes. PLC-β in turn hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to diacyl glycerol (DAG) and inositol trisphosphate...
- "Regulation of apoptosis by phosphatidylinositol 4,5-bisphosphate inhibition of caspases, and caspase inactivation of phosphatidylinositol phosphate 5-kinases"...
produce products that function as second messengers in signal transduction. Examples include phosphatidylinositol (4,5)-bisphosphate (PIP2), that can be...- the other chimera. Phosphatidylinositol-4-phosphate 3-kinase Phosphatidylinositol-4,5-bisphosphate 3-kinase Phosphatidylinositol-4-phosphate 5-kinase...
- below the levels of PtdIns4P (Phosphatidylinositol 4-phosphate and PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate). Notably, steady-state PtdIns5P...
Phospholipase C (section Biological function)Phospholipase C's role in signal transduction is its cleavage of phosphatidylinositol 4,5-bisphosphate (PIP2) into diacyl glycerol (DAG) and inositol 1,4,5-trisphosphate...
phospholipase enzyme (PLCE1) that catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to generate two second messengers: inositol 1,4,5-triphosphate...
interact with: Phosphatidylinositol 4-phosphate Phosphatidylinositol (4,5)-bisphosphate Phosphatidylinositol 3-phosphate Phosphatidylinositol 5-phosphate...- alpha(IIb)beta(3) on chymotrypsin-treated rabbit platelets decreases phosphatidylinositol 4,5-bisphosphate and increases cytoskeletal actin". Platelets. 10 (4): 228–37...
- inositol phospholipids in eukaryotes by hydrolyzing lipid phosphatidylinositol 4,5-bisphosphate and creating inositol 1,4,5-trisphosphate and diacylglycerol