Null Allele Examples

A null allele is a nonfunctional allele (a variant of a gene) caused by a genetic mutation. Such mutations can cause a complete lack of production of...

(polymorphism) present, or the proportion of heterozygotes in the population. A null allele is a gene variant that lacks the gene's normal function because it either...

alleles. A nullizygous organism carries two mutant alleles for the same gene. The mutant alleles are both complete loss-of-function or 'null' alleles...

variation within and between species are due to random genetic drift of mutant alleles that are selectively neutral. The theory applies only for evolution at...

(being partially or wholly inactivated). When the allele has a complete loss of function (null allele), it is often called an amorph or amorphic mutation...

genotypes − # alleles). The 5% significance level for 1 degree of freedom is 3.84, and since the χ2 value is less than this, the null hypothesis that...

of a particular gene (allele) in a given population to a situation where only one of the alleles remains. That is, the allele becomes fixed. In the absence...

four-or-more-digit number (e.g., HLA-B*08:01, A*68:01, A*24:02:01N N=Null) to designate a specific allele at a given HLA locus. HLA loci can be further classified...

in which a single copy of the wild-type allele at a locus in heterozygous combination with a variant allele is insufficient to produce the wild-type...

chromosome 2. Chromosomal translocation Cytogenetic notation Karyotype Null allele International System for Human Cytogenetic Nomenclature Wood, E.J. (1995)...

mutation occurs in the Fy-b allele and has been designated Fy-bEs (erythroid silent). Two isotypes have been identified. The Fy-x allele is characterized by a...

selection refers to a number of selective processes by which multiple alleles (different versions of a gene) are actively maintained in the gene pool...

segregation of chromosomes norm of reaction See reaction norm. null allele Any allele made non-functional by way of a genetic mutation. The mutation may...

For example, in order to test whether allele a is dominant over allele A, the choice t = (1, 1, 0) is locally optimal. To test whether allele a is recessive...

which alleles are dominant and which are recessive. For example, if the allele specifying tall stems in pea plants is dominant over the allele specifying...

of allele frequency change at a single gene locus under a broad range of conditions. Haldane also applied statistical analysis to real-world examples of...

frequency of heterozygous null alleles is much higher than expected, indicating a heterozygous advantage for TPI null alleles. The reason is unknown; however...

disorders. Clock mutant organisms can either possess a null mutation or an antimorphic allele at the Clock locus that codes for an antagonist to the wild-type...

The two common O alleles, O01 and O02, share their first 261 nucleotides with the group A allele A01. However, unlike the group A allele, a guanosine base...

the allele frequency. Fisher made no restrictive assumptions in his formula concerning fitness parameters, mate choices or the number of alleles and loci...