NF κB

B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription of DNA, cytokine production and cell survival. NF-κB...

Look up NF or nf in Wiktionary, the free dictionary. NF may refer to: NF (rapper), American hip hop musician NF (EP), 2014 Neurofibromatosis, a medical...

lymphocytes. The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...

degradation of I-κB. I-κB blocks the NLS of NF-κB therefore preventing its translocation to the nucleus. Once I-κB is degraded, it cannot bind to NF-κB and the...

normally binds to NF-κB and inhibits its translocation, is phosphorylated by IKK and subsequently degraded, releasing NF-κB. NF-κB is a heterodimeric...

protein promotes the continuous activation of a transcription factor, NF-κB. NF-κB controls the expression of various genes which increase the survival...

by the CHUK gene. IKK-α is part of the IκB kinase complex that plays an important role in regulating the NF-κB transcription factor. However, IKK-α has...

REL-associated protein involved in NF-κB heterodimer formation, nuclear translocation and activation [citation needed]. NF-κB is an essential transcription factor...

protein that cleaves A20, an inhibitory protein of NF-κB signaling (which acts by deubiquitylating NF-κB's ubiquitylation substrates, having an inhibitory...

derivatives are synthesized by regio/stereoselective Michael addition to ring A. NF-κB is a transcription factor that regulates many genes involved in cell survival...

in the inhibition of B cell proliferation. It is also known to induce NF-κB inhibitor IKBa, inhibiting NF-κB activation. NF-κB is a transcription factor...

H1-antihistamines can also reduce inflammation, since the expression of NF-κB, the transcription factor the regulates inflammatory processes, is promoted...

the 293T-based rapid retroviral production system and the cloning of the NF-κB p65/ RelA DNA regulatory factor. His areas of research include autoimmunity...

exhibit pathologically overactive NF-κB, PI3K/AKT/mTOR, JAK-STAT0, MAPK/ERK, B-cell receptor, toll-like receptor, and NF-κB signaling pathways and thereby...

(CRMO or Behçet disease) IL-1 mediated IFN-mediated Mediated by increased NF-κB activation Most proteins known to be involved in hereditary AIDs are involved...

and the 50 kD protein is a DNA binding subunit of the NF-kappaB (NF-κB) protein complex. NF-κB is a transcription factor that is activated by various...

addition, IκBα blocks the ability of NF-κB transcription factors to bind to DNA, which is required for NF-κB's proper functioning. The gene encoding...

monogenetic disease caused by mutation in the IKBKG gene (IKKγ, also known as the NF-κB essential modulator, or NEMO). NEMO is the modulator protein in the IKK...

survival. Akt also activates IKKα, which leads to NF-κB activation and cell survival. Active NF-κB induces the expression of anti-apoptotic genes such...

IκBα, and this inhibits NF-κB translocation to the nucleus. Pevonedistat, through its effects on NF-κB and a target of NF-κB (microRNA-155), prolonged...