Mutagenesis

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  • code. In nature mutagenesis can lead to cancer and various heritable diseases, and it is also a driving force of evolution. Mutagenesis as a science was...
  • and any gene products. Also called site-specific mutagenesis or oligonucleotide-directed mutagenesis, it is used for investigating the structure and biological...
  • Thumbnail for Saturation mutagenesis
    Site saturation mutagenesis (SSM), or simply site saturation, is a random mutagenesis technique used in protein engineering, in which a single codon or...
  • replicate, mutagenesis caused by viral infections is a fairly common occurrence. Not all integrating viruses cause insertional mutagenesis, however. Some...
  • Thumbnail for Mutagenesis (molecular biology technique)
    for the editing or mutagenesis of a genome in vivo. Site-directed mutagenesis has proved useful in situations that random mutagenesis is not. Other techniques...
  • Transposon mutagenesis, or transposition mutagenesis, is a biological process that allows genes to be transferred to a host organism's chromosome, interrupting...
  • Thumbnail for Cassette mutagenesis
    Cassette mutagenesis is a type of site-directed mutagenesis that uses a short, double-stranded oligonucleotide sequence (gene cassette) to replace a fragment...
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    ENU (redirect from ENU mutagenesis)
    significant spermatogonial mutagenesis in an SLT, although at a rate one-third of that of X-rays. Russell's earlier mutagenesis work on Drosophila using...
  • Thumbnail for Alanine scanning
    scanning method which combines the concepts of alanine scanning mutagenesis and binomial mutagenesis with phage display technology was used. Another critical...
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    substantial killing. A 5x10−4 per gene mutation rate observed in a typical EMS mutagenesis experiment of the model organism C. elegans, corresponds to a raw mutation...
  • Recursive ensemble mutagenesis then utilizes information from previous combinatorial cassette mutagenesis. Codon cassette mutagenesis allows you to insert...
  • DNA Repair and Mutagenesis is a college-level textbook about DNA repair and mutagenesis written by Errol Friedberg, Graham Walker, Wolfram Siede, Richard...
  • Site-Directed Mutagenesis and Synthetic Biology. The team's paper describing site-directed mutagenesis was published as "Mutagenesis at a Specific Position...
  • find all the essential genes of M. genitalium through global transposon mutagenesis. As a result, they found that 382 out of 482 protein coding genes were...
  • recBCD, was necessary for the directed mutagenesis observed by Cairns and colleagues in 1989. The directed mutagenesis hypothesis was challenged in 2002,...
  • asymmetric PCR could be used to improved the efficiency of site-directed mutagenesis. Besides the introduction of mutations, Overlap Extension PCR is widely...
  • Mechanisms of Mutagenesis (ISSN 0027-5107, impact factor 2020: 2.433) Mutation Research/Genetic Toxicology and Environmental Mutagenesis (ISSN 1383-5718...
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    site-directed mutagenesis to create point mutations and measure relative fitness of each mutant. In Escherichia coli, one study used transposon mutagenesis to directly...
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    Sun Z, Townsend K, et al. (October 1999). "A large-scale insertional mutagenesis screen in zebrafish". Genes & Development. 13 (20): 2713–2724. doi:10...
  • adopted by Lawrence Loeb and colleagues to describe the strategy of lethal mutagenesis to cure HIV by using mutagenic ribonucleoside analogs. There was an earlier...
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