Genetics Silencer Functionality
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In genetics, a silencer is a DNA sequence capable of binding transcription regulation factors, called repressors. DNA contains genes and provides the template...
A silencer, also known as a sound suppressor, suppressor, or sound moderator, is a muzzle device that suppresses the blast created when a gun (firearm...- Glossary of cellular and molecular biology (0–L) (redirect from Glossary of genetics)of cell biology, molecular biology, and related disciplines, including genetics, biochemistry, and microbiology. It is split across two articles: This...
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the...
then helps to recruit the RNA polymerase to the promoter; conversely silencers bind repressor proteins and make the DNA less available for RNA polymerase...- or recovery of a mutant gene to its normal functionality, especially in the context of experimental genetics, where an experiment (e.g. a drug, cross,...
RNA splicing (redirect from Splicing (genetics))splicing silencer (ISS), Exonic splicing enhancer (ESE), and Exonic splicing silencer (ESSE3). Solution structure of Intronic splicing silencer and its...- Mutation (redirect from Reversion (genetics))non-coding regulatory sequences of a gene, such as promoters, enhancers, and silencers, can alter levels of gene expression, but are less likely to alter the...
In genetics, an enhancer is a short (50–1500 bp) region of DNA that can be bound by proteins (activators) to increase the likelihood that transcription...- Cis-regulatory element (section Silencers)including -but not limited to- locus control regions, promoters, enhancers, silencers, boundary control elements and other modulators. Cis-regulatory modules...
- Transcription (biology) (redirect from Transcription (genetics))distant from the transcription start sites. These include enhancers, silencers, insulators and tethering elements. Among this constellation of elements...
- enhancer and silencer sequences that further modify the activity of promoters by binding activator or repressor proteins. Enhancers and silencers may be distantly...
RE1-silencing transcription factor (redirect from Neuron-Restrictive Silencer Factor)RE1-Silencing Transcription factor (REST), also known as Neuron-Restrictive Silencer Factor (NRSF), is a protein which in humans is encoded by the REST gene...- canonical histone mRNAs: life without a poly(A) tail". Nature Reviews. Genetics. 9 (11): 843–54. doi:10.1038/nrg2438. PMC 2715827. PMID 18927579. Berg...
- Review of Genetics. 47: 275–306. doi:10.1146/annurev-genet-021313-173730. PMID 24016189. McNally FJ, Rine J (November 1991). "A synthetic silencer mediates...
in the intron itself (intronic splicing silencers, ISS) or in a neighboring exon (exonic splicing silencers, ESS). They vary in sequence, as well as...- SNP annotation (section Functional annotation)interaction between enhancer/silencer and its target gene. Alternative splicing is one of the most important components that show functional complexity of genome...
expression can also be controlled by repressor proteins that attach to silencer regions of the DNA and prevent that region of the DNA code from being expressed...
Gene expression (redirect from Expression (genetics))directly causing degradation of the transcript. The 3′-UTR also may have silencer regions that bind repressor proteins that inhibit the expression of a mRNA...
DNase I hypersensitive site (category Genetics)of cis-regulatory elements including promoters, enhancers, insulators, silencers and locus control regions. A high-throughput measure of these regions...
- repressor binds to the silencer site, it reduces the chance that a site close-by will be chosen as a splicing junction. These silencer sites can be found