Dna Chemical modifications and altered DNA packaging
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influenced by how the DNA is packaged in chromosomes, in a structure called chromatin. Base modifications can be involved in packaging, with regions that...
Nucleosome (redirect from Histone post-translational modification)structural unit of DNA packaging in eukaryotes. The structure of a nucleosome consists of a segment of DNA wound around eight histone proteins and resembles thread...
signal or perpetuate altered activity states." This definition would be inclusive of transient modifications associated with DNA repair or cell-cycle...- DNA damage is an alteration in the chemical structure of DNA, such as a break in a strand of DNA, a nucleobase missing from the backbone of DNA, or a...
relevant modifications to the genome that do not involve a change in the nucleotide sequence. Examples of such modifications are changes in DNA methylation...- Chromatin (section Chromatin and DNA repair)Chromatin is a complex of DNA and protein found in eukaryotic cells. The primary function is to package long DNA molecules into more compact, denser structures...
sugar-phosphate backbone of the DNA, and are therefore largely independent of the base sequence. Chemical modifications of these basic amino acid residues...- The term modifications in genetics refers to both naturally occurring and engineered changes in DNA. Incidental, or natural mutations occur through errors...
Histone (redirect from Histone modification)between the positively charged histones and negatively charged phosphate backbone of DNA. Histones may be chemically modified through the action of enzymes...- created proteins and polysaccharides undergo chemical modifications such as phosphorylation and glycosylation, which are used as packaging signals to direct...
- Chromatin remodeling (section Response to DNA damage)in DNA is in part regulated by chemical modifications to histone proteins, primarily on their unstructured ends. Together with similar modifications such...
CRISPR gene editing (section Comparison to DNA editing)This modification inhibits transcription. These precisely placed modifications may then be used to regulate the effects on gene expressions and DNA dynamics...
Human genome (redirect from Human DNA)chromatin packaging, histone modifications and DNA methylation, and which are important in regulating gene expression, genome replication and other cellular...
Gene (section DNA replication and cell division)Proteins Ch 4: DNA and Chromosomes 4.1: The Structure and Function of DNA 4.2: Chromosomal DNA and Its Packaging in the Chromatin Fiber Ch 5: DNA Replication...- a series of post-transcriptional modifications. metabolism The complete set of chemical reactions which sustain and account for the basic processes of...
- Epigenomics (section DNA methylation)are the study of the genome and proteome of a cell. Epigenetic modifications are reversible modifications on a cell's DNA or histones that affect gene...
CRISPR (category Repetitive DNA sequences)phage DNA packaging. In the second mechanism PICI CpmAB redirects the phage capsid morphogenetic protein to make 95% of SaPI-sized capsid and phage DNA can...- Genetics (section DNA and chromosomes)1038/nature04727. PMID 16710414. Alberts et al. (2002), II.4. DNA and chromosomes: Chromosomal DNA and Its Packaging in the Chromatin Fiber Archived 18 October 2007...
Biology (redirect from Chemical basis of life)classical genetics. In the 1940s and early 1950s, a series of experiments by Alfred Hershey and Martha Chase pointed to DNA as the component of chromosomes...
themselves in the minor grooves of the DNA and extend through the double helix, which leaves them open for modifications involved in transcriptional activation...
- of Food Safety Assessment of Foods Derived from Recombinant-DNA Plants (CAC/GL 45-2003);and (c) encourage the entity to share information referred to in
- by normal cellular processes, and its in vivo half-life can be regulated through the use of various modifications and delivery methods. The inherent
- Gilbert developed a DNA sequencing method based on chemical modification of DNA and subsequent cleavage at specific bases. Although Maxam and Gilbert published