Brca Mutation Health effects - Search results - Wiki Brca Mutation Health Effects
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A BRCA mutation is a mutation in either of the BRCA1 and BRCA2 genes, which are tumour suppressor genes. Hundreds of different types of mutations in these... |
Olaparib (section Side effects) the brand name Lynparza, is a medication for the maintenance treatment of BRCA-mutated advanced ovarian cancer in adults. It is a PARP inhibitor, inhibiting... |
DNA double-strand breaks. If BRCA1 or BRCA2 itself is damaged by a BRCA mutation, damaged DNA is not repaired properly, and this increases the risk for... |
Oophorectomy (section Risks and adverse effects) "Challenging and Complex Decisions in the Management of the BRCA Mutation Carrier". Journal of Women's Health. 22 (10): 825–834. doi:10.1089/jwh.2013.4407. PMC 4047843... |
Talazoparib (section Side effects) by Pfizer for the treatment of advanced breast cancer with germline BRCA mutations. Talazoparib is similar to the first in class PARP inhibitor, olaparib... |
DNA damage theory of aging (redirect from Genetic mutation theory of aging) by Kutluk Oktay, MD, PhD based on his observations that women with BRCA mutations produced fewer oocytes in response to ovarian stimulation repair. His... |
not been established, and "insignificant mutation", referring to a gene variant that has no impact on the health or function of an organism. The term "variant'... |
Genetic disorder (redirect from Hereditary mutation) genetic mutations to a small proportion of cells in the body, are acquired diseases. Some cancer syndromes, however, such as BRCA mutations, are hereditary... |
diagnosed with BRCA mutations, as well as that, recent studies show that men with increased risks of developing prostate cancer due to BRCA mutations can decrease... |
Niraparib (section Side effects) deleterious BRCA mutation in the germline was 21.0 months under niraparib therapy, as compared to 5.5 months under placebo. Patients without such a mutation had... |
Alejandra Campoverdi (section Women's health advocacy) with Penn Medicine's Basser Center for BRCA, which is the first awareness campaign on the BRCA gene mutation that targets Latinos and offers Spanish-language... |
those with BRCA-1 and BRCA-2 genetic abnormalities are at increased risk. The major genetic risk factor for ovarian cancer is a mutation in BRCA1 or... |
Genetic testing (redirect from Targeted mutation analysis) health and trait-related information, or both. There are a variety of DTC genetic tests, ranging from tests for breast cancer alleles to mutations linked... |
Talazoparib was approved in 2018 by US FDA for breast cancer with germline BRCA mutations. The main function of radiotherapy is to produce DNA strand breaks,... |
Prophylactic salpingectomy (section Long-term effects) salpingectomy. High-Grade Serous Carcinoma (HGSC) is usually driven by BRCA gene mutations – it was hypothesised that a decrease risk of ovarian cancer observed... |
Predictive medicine (section Health benefits) "BRCA Gene Mutations: Cancer Risk and Genetic Testing Fact Sheet - National Cancer Institute". 25 November 2020. "Emory-Georgia Tech Predictive Health... |
Healthcare in Pakistan (redirect from Health Care and Pakistan) breast and ovarian cancer. The genetic findings show that BRCA mutation (BRCA1 and BRCA2) mutations account for a substantial proportion of hereditary breast/ovarian... |
disease-causing mutation is the proportion of individuals with the mutation that exhibit clinical symptoms among all individuals with such mutation. For example:... |
Gynecologic cancer (category Women's health) PMID 23404857. Neff, Robert T.; Senter, Leigha; Salani, Ritu (August 2017). "BRCA mutation in ovarian cancer: testing, implications and treatment considerations"... |
Gynecologic oncology (category Women's health) PMID 23404857. Neff, Robert T.; Senter, Leigha; Salani, Ritu (August 2017). "BRCA mutation in ovarian cancer: testing, implications and treatment considerations"... |