Heroin: Chemical compound; opioid most commonly used as a recreational drug for its euphoric effects

Heroin is a drug.

It is also known as Diacetylmorphine or Diamorphine. Heroin was originally a trade name. It is an opioid - a type of drug which acts like morphine in the body. Heroin is called a semi-synthetic opioid. This means it is made from an opiate that occurs in nature. For Heroin, that natural opiate is morphine.

Heroin
Heroin: Legality, Signs of an Overdose[11], Detoxification
Heroin: Legality, Signs of an Overdose[11], Detoxification
Clinical data
PronunciationHeroin: /ˈhɛrɪn/
SynonymsDiacetylmorphine, acetomorphine, (dual) acetylated morphine, morphine diacetate, Diamorphine (BAN UK)
AHFS/Drugs.comheroin
Dependence
liability
High
Addiction
liability
High
Routes of
administration
Intravenous, inhalation, transmucosal, by mouth, intranasal, rectal, intramuscular, subcutaneous, intrathecal
Drug classOpioid
ATC code
Legal status
Legal status
  • AU: S9 (Prohibited substance)
  • CA: Schedule I
  • DE: Anlage I, II and III
  • NZ: Class A
  • UK: Class A
  • US: Schedule I
  • UN: Narcotic Schedules I and IV
Pharmacokinetic data
Bioavailability<35% (by mouth), 44–61% (inhaled)
Protein binding0% (morphine metabolite 35%)
MetabolismLiver
Onset of actionWithin minutes
Elimination half-life2–3 minutes
Duration of action4 to 5 hours
Excretion90% kidney as glucuronides, rest biliary
Identifiers
IUPAC name
  • (5α,6α)-7,8-didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol diacetate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEBI
ChEMBL
ECHA InfoCard100.008.380 Edit this at Wikidata
Chemical and physical data
FormulaC21H23NO5
Molar mass369.42 g·mol−1
3D model (JSmol)
SMILES
  • CC(OC1=C(O[C@@H]2[C@]34CCN(C)[C@@H]([C@@H]4C=C[C@@H]2OC(C)=O)C5)C3=C5C=C1)=O
InChI
  • InChI=1S/C21H23NO5/c1-11(23)25-16-6-4-13-10-15-14-5-7-17(26-12(2)24)20-21(14,8-9-22(15)3)18(13)19(16)27-20/h4-7,14-15,17,20H,8-10H2,1-3H3/t14-,15+,17-,20-,21-/m0/s1 checkY
  • Key:GVGLGOZIDCSQPN-PVHGPHFFSA-N checkY
  (verify)
Heroin: Legality, Signs of an Overdose[11], Detoxification
When heroin was first made (around 1900), it was sold as a cough medicine and a painkiller. It was marketed in bottles like this one
Heroin: Legality, Signs of an Overdose[11], Detoxification
Heroin for medical use in hospitals, as a painkiller. It is in liquid form, so it can be given with a syringe (needle)
Heroin: Legality, Signs of an Overdose[11], Detoxification
A patient being injected with Heroin at a hospital.

Heroin is a white or brown powder made from the sap of the poppy plant. It is a painkiller. A painkiller is an analgesic drug. Its effects are like other drugs that come from the poppy plant sap. These include opium and morphine.

People smoke or inject heroin to get a calm feeling of relaxation. It is commonly known as "being high". The extreme happiness is known as euphoria. Heroin is a very addictive drug. This means that once a person starts taking heroin, they will want to take more and more. In some cases, they will want to continue even when they know it is making them sick and harming them. Heroin is an illegal drug in many countries, unless it is used to treat a medical problem.

Drugs like cocaine, marijuana, and heroin have been decriminalized in numerous countries. To date, these include somewhere between 25 and 30 countries.

Legality

It is illegal to make, sell, and use heroin in most countries, unless a doctor has prescribed it to a person to treat a medical problem. Many people smuggle heroin and sell it illegally on the streets to make money.

Effects

If people use heroin, they may overdose (take too much), which can make them very sick or even kill them.

When people take heroin, they get "high," or intoxicated (like being drunk on alcohol). When a person is intoxicated, they can get hurt if they drive a car or other vehicle. Also, when a person is intoxicated, they may do dangerous things, like having unsafe sex or being violent towards others.

Another danger is "withdrawal", which can happen when a person stops using heroin. As with other addictions, withdrawal is a painful, unpleasant process that involves physical and mental symptoms. Withdrawal is most common when people stop using heroin suddenly, or when a person who has been using heroin for a while tries to stop. However, a person can have withdrawal symptoms even after using heroin for just 3 days. Physical symptoms often include bad body aches, hot and cold sweats, chills, restlessness, diarrhea, and problems with eating and sleeping. These withdrawal symptoms are sometimes called cold turkey. Sometimes withdrawal feels like a very bad case of the flu. People can also have very strong psychological symptoms of withdrawal, like depression and strong cravings for heroin. Many heroin users are very afraid of withdrawal. Withdrawal - and fear of withdrawal - is one of the most common reasons why people have trouble quitting heroin. Medications like methadone and Suboxone are sometimes used to treat or prevent withdrawal symptoms, and to decrease cravings for heroin.

Injecting heroin can be very dangerous. A person can get infections by using a needle that has not been cleaned properly. People who share the same needle can infect each other with diseases that travel in the blood, like HIV or hepatitis C. They can also do other dangerous things while high on heroin.

Signs of an Overdose

  • Extremely shallow and slow breathing.
  • Clammy skin.
  • Profound confusion.
  • Convulsions.
  • Cyanosis (bluish tint) of the fingernails and lips.
  • Dangerously slowed heart rate.
  • Coma.
  • Death.

Detoxification

The primary objective of detoxification is to help the addict overcome a state of physical dependence on heroin by allowing time for the heroin and related toxins to exit the body. The body will adjust to the lack of heroin by reacting in various ways which may include pain, nausea, vomiting, diarrhea, insomnia and other withdrawal symptoms. During detox, the patient will be provided with medications, therapy and treatment that will help to ease or eliminate withdrawal symptoms in a safe and effective manner.

While detox is not actually a treatment for heroin addiction because it only focuses on providing treatment for the physical dependence that surrounds the addiction and does not place any focus on the psychological elements of the chemical dependency, it is a necessary first step to the recovery process. When detoxification is the first step of a lengthy heroin addiction treatment process which includes counseling and behavioral therapy, the process often leads to long-term success in recovery from heroin addiction.

Street names

There are many slang names, or street names, for heroin. These names are different in different places. Some of the most common are Dope, Horse, Junk, H, Brown, Black Magic, Juice and Smack, number 4.

Heroin history

In 1874, an English researcher, C.R. Wright, first synthesized heroin by boiling morphine and acetic anhydride. His early testing of heroin – then known as diacetylmorphine – showed undesirable side effects such as anxiety, sleepiness and vomiting immediately following administration. Accordingly, he discontinued his research.

Over 20 years later in 1895, German scientist Heinrich Dreser and his colleagues at the pharmaceutical company Bayer continued Wright’s studies and declared diacetylmorphine successful in treating many common respiratory ailments.

Heroin was first made in 1898, by the Bayer Company in Germany. At first, it was used as a cough medicine and a painkiller. People thought that heroin would help decrease morphine and opium addiction. But after twelve years, doctors realized that people became strongly addicted to heroin. In 1914, the United States passed the Harrison Act. This was the first of many attempts to control the use of narcotics.

The word heroin comes from the German word heroisch, which means powerful and heroic.

References

Tags:

Heroin LegalityHeroin Signs of an Overdose[11]Heroin DetoxificationHeroin Street namesHeroin historyHeroinDrugMorphineOpioidTrade name

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