Sam

• Sam, Benin
• Sam, Boulkiemdé, Burkina Faso
• Sam, Bourzanga, Burkina Faso
• Sam, Kongoussi, Burkina Faso
• Sam, Iran
• Sam, Teton County, Idaho, United States, a populated place

• Sam (given name), a list of people and fictional characters with the given name or nickname
• Sam (surname), a list of people with the surname
  • Cen (surname) (岑), romanized "Sam" in Cantonese
  • Shen (surname) (沈), often romanized "Sam" in Cantonese and other languages
• Samwise Gamgee, usually referred to as Sam, a character in The Lord of the Rings.

• Sam (Book of Mormon), elder brother of Nephi
• Sām, a Persian mythical folk hero
• Sam Ziwa, an uthra (angel or celestial being) in Mandaeism
• Sam, Shem in Islam

• Sam (army dog) (died 2000)
• Sam (horse) (b 1815), British Thoroughbred
• Sam (koala) (died 2009), rescued after 2009 bush fires in Victoria, Australia
• Sam (orangutan), in the movie Dunston Checks In
• Sam (ugly dog) (1990–2005), voted the world's ugliest dog in 2003, 2004, and 2005
• Unsinkable Sam (died 1955), a cat which survived the sinking of three ships during World War II

• Sam (1967 film), a 1976 film directed by Larry Buchanan
• Sam (1986 film), a 1986 documentary film
• Sam (2021 film), a 2021 film directed by Yan England
• Sam (Osvajači album), 1995
• Sam (Škabo album), 2003
• "Sam" (Olivia Newton-John song), 1977
• Sam (1973 TV series), a British drama
• Sam (1978 TV series), a US crime drama
• Sam (Goodman novel), a 2023 novel by Allegra Goodman
• SAM Awards, for South Australian Music Awards

Brands and enterprises

• SAM (vehicles), a Greek truck manufacturer
• S.A.M.: Simply About Music, a satellite-driven radio network
• SAM, stock ticker of Boston Beer Company, the brewers of Samuel Adams beer
• SAM Colombia, a Colombian airline
• SAM Records, an American disco/post-disco record company
• Società Aerea Mediterranea, an Italian airline 1926-1934 and 1959-1981

Business terminology

• Serviceable available market
• Shared appreciation mortgage
• Social accounting matrix of transactions in an economy
• System for Award Management (SAM), U.S. Government supplier database

• Sam languages, comprising Somali, Rendille and Boni
• Sam language of New Guinea
• Samaritan Aramaic language, an extinct liturgical language (ISO 639-2, 639-3 code: sam)

• Seattle Art Museum
• Singapore Art Museum
• SAM, museum code for the South Australian Museum

• Sahabat Alam Malaysia, an environmental NGO based in Malaysia
• Scientific Advice Mechanism of the European Commission
• Serve America Movement, an American political party
• Snowmobile Association of Massachusetts
• Society of American Magicians

Biology, chemistry and medicine

• Phytelephas seemannii, known in Cuna as 'sam'
• S-Adenosyl methionine, a common co-substrate involved in methyl group transfers
• SAM, a candidate phylum of bacteria
• Sustained Acoustic Medicine, a medical treatment for arthritis
• SAMtools (for Sequence Alignment Map), a data storage format for DNA sequencing
• Self-assembled monolayer of amphiphilic molecules
• Shoot apical meristem, a plant tissue
• Significance analysis of microarrays, in DNA microanalysis
• Spore photoproduct lyase, an enzyme
• Sorting and assembly machinery, a protein complex in the outer mitochondrial membrane
• Segmental arterial mediolysis, a medical condition affecting the arteries

Physics and astronomy

• Southern Annular Mode of southern hemisphere atmospheric variability
• Swinging Atwood's machine
• SAm, an unbarred Magellanic spiral galaxy

Software and computing

• SAM (file format) or Sequence Alignment Map, a data format used in bioinformatics
• Sam (text editor)
• SAM Coupé, an 8-bit British home computer
• Microsoft Sam, a voice for the screen reader in Windows 2000 and XP
• SAM, a New Zealand chatbot that discuss politics
• SAM Lock Tool, better known as Syskey
• Sequential access memory
• Simple Anonymous Messaging, a protocol specification used in the I2P network layer
• Simulation for Automatic Machinery, two minicomputers
• Single Abstract Method, a programming structure, also known as a functional interface
• Software asset management
• Software Automatic Mouth, speech synthesis program
• Synchronous Address Multiplexer, a chip in some 8-bit computers; see Color Computer § SAM
• Syriac Abbreviation Mark, a Unicode control character

Security

• SAM card (Security Authentication Module card), holding cryptographic keys
• Secure access module
• Security Account Manager in Microsoft Windows

Other

• Scanning acoustic microscope
• Sample Analysis at Mars, on the Curiosity rover
• Scanning Auger microscope in Auger electron spectroscopy
• Scheduled Ancient Monument, commonly used name for British archaeological designation
• Small article monitor, screening for radioactive contamination
• Sparse antimagic square, in mathematics
• Stop action magnet in a pipe organ
• Surface-to-air missile, a type of missile

• Sam (mascot), 1984 Summer Olympics
• Strongside linebacker, gridiron football nickname
• Sam Maguire Cup, often known as "Sam", of the All-Ireland Senior Football Championship in gaelic football

• Tropical Storm Sam, various storms named Sam
• Sandy Area Metro, Oregon, US
• Sam FM (disambiguation)
• Schule am Meer (S.a.M. or SaM), a former boarding school in Juist, East Frisian islands, Free State of Prussia, German Reich
• Special administrative measures, in US law
• Split attraction model, a psychology model about sexual orientation
• Sam, in Indian classical music, the first count of a tala
• SAM, IATA airport code for Salamo Airport in Papua, New Guinea
• SAM, IOC and FIFA country code for Samoa

• Uncle Sam, a personification of the US government
• Samsø, earlier Samsey, literally "Sam's island"
• Sam. (disambiguation)