Teenretrovirale Middel
'n Teenretrovirale middel is enige medikasie wat gebruik word om die retrovirus MIV wat vigs veroorsaak te bestry.
Vaste-dosis kombinasies
Dit is 'n mengsel van verskeie teenretrovirale middels saamgevoeg in 'n enkele tablet, om as 'n een-per-dag-dosis geneem te word.
| Handelsnaam | Geneesmiddelnaam | Goedgekeur deur FDA in VSA | Maatskappy |
|---|---|---|---|
| "Combivir" | Sidovudien + lamivudien | 26 September 1997 | GlaxoSmithKline |
| "Trizivir" | Abakavir + sidovudien + lamivudien | 15 November 2000 | GlaxoSmithKline |
| "Aluvia" tablette "Kaletra" orale oplossing | Lopinavir/ritonavir | 15 September 2000 | Abbott Laboratories |
| "Epzicom" (in VSA) "Kivexa" (in Europa) | Abakavir + lamivudien | 2 Augustus 2004 | GlaxoSmithKline |
| "Truvada" | Tenofovir/emtrisitabien | 2 Augustus 2004 | Gilead Sciences |
| "Atripla" "Odimune" | Efavirens/emtrisitabien/tenofovir | 12 Julie 2006 | Gilead Sciences/Bristol-Myers Squibb Cipla |
| "Complera" | Rilpivirien + tenofovir/emtrisitabien | 10 Augustus 2011 | Gilead Sciences en Tibotec (Johnson & Johnson) |
| "Stribild" | Elvitegravir + cobicistat + tenofovir/emtrisitabien | 27 Augustus 2012 | Gilead Sciences |
| "Trivicay" | Tenofovir, lamivudien en dolutegravir | 12 Augustus 2013 | GlaxoSmithKline |
In Augustus 2012 is die verkose eerste-linie terapie in die VSA:
- Tenofovir/emtrisitabien ('n kombinasie van twee NRTIs) en efavirens ('n NNRTI).
- Tenofovir/emtrisitabien en raltegravir
- Tenofovir/emtrisitabien, ritonavir, en darunavir (die laaste twee is protease-ensiemremmers)
- Tenofovir/emtrisitabien, ritonavir, en atazanavir (die laaste twee is protease-ensiemremmers).
In Augustus 2019 is die verkose eerste- en tweedelinie terapie in die VSA en Suid-Afrika:
- Tenofovir, lamivudien en dolutegravir. Lg. vervang efavirens in die trippelkombinasieterapie.
Verwysings
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| Hierdie artikel is in sy geheel of gedeeltelik vanuit die Engelse Wiki vertaal. |
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